The Burnham Road at South Woodham Ferrers, the A132, is currently blocked in both directions.
The blockage is between the Rettendon turnpike and the Shaw Farm roundabout, on Ferrers Road.
There have been two separate incidents on the stretch of road, blocking the road both ways, which started before 7.50am this morning.
One was a serious collision between a car and a motorbike.
The road is now closed in both directions and queues are building on Woodham Road between Rettendon and South Woodham Ferrers.
There also delays in South Woodham Ferrers and queues southbound on Main Road towards Rettendon turnpike roundabout.
The road is likely to remain closed while emergency services deal with the situation.
Motorists are advised to avoid the area and take alternative routes.